The most prominent economic transformation in the past fifty years has been the remarkable progress of East Asian societies despite war, unrest, and the lack of any industrial foundation in their not-so-distant past. Numerous studies have been conducted on this topic, and various results have been reported, yet no coherent model exists in this regard. This research aims to provide an overall perspective and design a coherent model based on the effective experiences of selected East Asian countries in utilizing strategic opportunities for the benefit of other nations. This study is an example of a metasynthesis using the Sandelowski and Barroso method, which is included in content analysis studies. It is categorized as applied research in terms of its goal and descriptive research in terms of data collection. Based on the findings, 110 components were extracted within 14 domains and 4 dimensions, and the final results were presented in the form of a conceptual model. According to the research results, a model for managing strategic opportunities was provided. It was determined that the outcomes of strategic opportunity management, resulting from government intervention, infrastructure reform, industry and trade development, and human resource empowerment, have led to the economic development of East Asian industrial and commercial countries.