The value of the innovation process in organizations and societies, as well as economic growth with minimal environmental disruption, is a critical and essential policy. Addressing this issue has led various organizations worldwide to adopt the circular economy approach to utilize natural resources in an innovative manner within the industry and minimize waste. Therefore, the aim of this research is to propose a framework for designing the industrial innovation process with a circular economy approach. This study was conducted using the meta-synthesis method and the seven-step model of Sandelowski and Barroso, systematically reviewing 62 relevant articles from a total of 305 articles published between 2010 and 2023. The articles were selected based on inclusion criteria, and the validity of the research was confirmed through meetings held by the research team and an audit of the entire process to achieve consensus. The reliability was also verified using the Critical Appraisal Skills Programme (CASP) and Cohen's kappa coefficient, which yielded a reliability score of 0.781. The main dimensions of the study were designed and presented in a comprehensive conceptual model based on five categories and paradigmatic themes aligned with the innovation process derived from the extracted sources. The results of this study can serve as a basis for operationalizing the industrial innovation process in alignment with circular economy strategies and categories related to sustainable development at the level of industrial organizations.